Severe falciparum malaria in pregnancy in Southeast Asia: a multi-centre retrospective cohort study.
Makoto SaitoAung Pyae PhyoCindy ChuStephane ProuxMarcus J RijkenCandy BeauHtun Htun WinLaypaw ArchasuksanJacher WiladphaingernNguyen H PhuTran T HienNick P DayArjen M DondorpNicholas J WhiteFrançois NostenRose McGreadyPublished in: BMC medicine (2023)
Vital organ dysfunction in pregnant women with severe malaria was associated with a very high maternal and foetal mortality whereas severe anaemia or hyperparasitaemia alone were not associated with poor prognosis, which may explain the variation of reported mortality from severe malaria in pregnancy. Access to antenatal care must be promoted to reduce barriers to early diagnosis and treatment of both malaria and anaemia.
Keyphrases
- poor prognosis
- plasmodium falciparum
- early onset
- preterm birth
- pregnant women
- pregnancy outcomes
- long non coding rna
- healthcare
- cardiovascular events
- palliative care
- drug induced
- oxidative stress
- cardiovascular disease
- physical activity
- coronary artery disease
- pain management
- quality improvement
- iron deficiency
- birth weight
- affordable care act
- weight gain