Systematic Analysis of tRNA-Derived Small RNAs Reveals the Effects of Xuefu-Zhuyu Decoction on the Hippocampi of Rats after Traumatic Brain Injury.

Feng DaiTao TangRuohuang LuPengfei LiDandan FengMingrui HuYang Wang Pingping Gan

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

Our work successfully illuminates the efficiency of XFZYD in the treatment of TBI. The experimental data revealed AS-tDR-002004 and AS-tDR-002583 as potential targets for XFZYD therapy and showed that they influenced TBI via the cadherin signaling pathway, cocaine addiction, circadian entrainment, and the nicotine pharmacodynamics pathway in a TBI rat model.

Keyphrases

traumatic brain injury
severe traumatic brain injury
signaling pathway
mild traumatic brain injury
smoking cessation
single cell
stem cells
big data
replacement therapy
induced apoptosis
risk assessment
bone marrow
cell adhesion
prefrontal cortex