The miR-19a/Cylindromatosis Axis Regulates Pituitary Adenoma Bone Invasion by Promoting Osteoclast Differentiation.

Zhuowei LeiQuanji WangQian JiangHuiyong LiuLinpeng XuHonglei KangFeng LiYimin HuangTing Lei

Published in: Cancers (2024)

To summarize, the results of this study indicate that PA-derived miR-19a promotes osteoclastogenesis by inhibiting CYLD expression and enhancing the activation of the NF-кB and MAPK pathways.

Keyphrases

signaling pathway
long non coding rna
cell proliferation
bone loss
poor prognosis
long noncoding rna
pi k akt
lps induced
oxidative stress
bone mineral density
inflammatory response
toll like receptor
bone regeneration