The curvature quantification of wave I in auditory brainstem responses detects cochlear synaptopathy in human beings.
Florian Herrmann SchmidtAlexander DörmannKarsten EhrtWilma GrossmannRobert MlynskiLichun ZhangPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2024)
The curvature at the peak of wave I is the most sensitive metric for detecting cochlear synaptopathy in humans and may be applied in routine diagnostics to detect early degenerations of the auditory nerve.