Darunavir/cobicistat showing similar effectiveness as darunavir/ritonavir monotherapy despite lower trough concentrations.

Alicia Gutiérrez-ValenciaMaria Trujillo-RodriguezTamara Fernandez-MagdalenoNuria EspinosaPompeyo VicianaLuis F López-Cortés

Published in: Journal of the International AIDS Society (2019)

DRV Ctrough was lower in HIV-infected subjects receiving DRVcobi than with DRVrtv . However, this did not appear to influence the efficacy of DRVcobi , when administered as monotherapy.

Keyphrases

hiv infected
antiretroviral therapy
hiv infected patients
combination therapy
open label
human immunodeficiency virus
randomized controlled trial
systematic review
clinical trial