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Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma.
Kunyuan Wang
Qianting Lu
Yufeng Luo
Ganxiang Yu
Zhilei Wang
Jiaen Lin
Zhenlin Tan
Yueqiong Lao
Shiming Liu
Hui Yang
Published in:
Biology direct (2024)
Circ_MAPK9, as an oncogene, promotes HCC growth and metastasis through miR-642b-3p/STAT3-LDHA axis. Circ_MAPK9 could serve as a potential biomarker for HCC poor prognosis and diagnosis.
Keyphrases
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poor prognosis
signaling pathway
long non coding rna
pi k akt
oxidative stress
cell proliferation
binding protein