Metabolic syndrome emerges after artificial selection for low baroreflex sensitivity.
Li-Li ZhangYing ZhangYan-Qiong ChengJing-Ming ZhangHong-Qi LiuWei-Zhong WangJawahar L MehtaZhi-Gang XiongDing-Feng SuAi-Jun LiuPublished in: CNS neuroscience & therapeutics (2018)
Our study demonstrated that intrinsic low BRS induced hypertension and metabolic disorder. Restoration of impaired BRS might be a potent target of therapeutic intervention in metabolic syndrome.