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Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype.

Xingdong GuoLehui DuNa MaPei ZhangYuan WangYanan HanXiang HuangQian ZhangXin TanXiao LeiBaolin Qu
Published in: Journal of translational medicine (2022)
MPLA is a novel treatment strategy for RILI. Exosomes derived from macrophages are key to the radioprotective role of MPLA in RILI.
Keyphrases
  • radiation induced
  • radiation therapy
  • mesenchymal stem cells
  • stem cells
  • mouse model
  • fatty acid
  • replacement therapy