Trends in clinical presentation of children with COVID-19: a systematic review of individual participant data.
Briana ChristophersBenjamin Gallo MarinRocío OlivaWeston T PowellTimothy J SavageIan C MichelowPublished in: Pediatric research (2020)
This systematic review revealed that the majority of children with COVID-19 presented with either no symptoms or a single, non-respiratory symptom. By using an independent participant data approach, this analysis underscores the challenge of diagnosing COVID-19 in pediatric patients due to the wide variety of symptoms and seemingly poor correlation of imaging findings with symptomatic disease. The data presented from individual patients from case series or cohort studies add more granularity to the current description of pediatric COVID-19.
Keyphrases
- coronavirus disease
- sars cov
- systematic review
- electronic health record
- young adults
- big data
- respiratory syndrome coronavirus
- end stage renal disease
- ejection fraction
- newly diagnosed
- high resolution
- data analysis
- randomized controlled trial
- single cell
- mass spectrometry
- physical activity
- depressive symptoms
- patient reported outcomes
- fluorescence imaging
- childhood cancer