Fatty acid oxidation is critical for the tumorigenic potential and chemoresistance of pancreatic cancer stem cells.
Marta MascaraqueSarah CourtoisAlba Royo-GarcíaDavid BarnedaAndrei M StoianIsabel VillaosladaPilar Espiau-RomeraAnsooya BokilAndrés Cano-GalianoPetra JagustChristopher HeeschenPatricia SanchoPublished in: Journal of translational medicine (2024)
Targeting FAO inhibition represents a promising therapeutic strategy against this highly tumorigenic population.