Bifidobacterium Lactis Probio-M8 regulates gut microbiota to alleviate Alzheimer's disease in the APP/PS1 mouse model.

Jianing CaoWilliam Kwame AmakyeChunli QiXiaojun LiuJie MaJiaoyan Ren

Published in: European journal of nutrition (2021)

Our results demonstrated that Probio-M8 reduced Aβ plaque burden in the whole brain and protected against gut microbiota dysbiosis. Furthermore, Probio-M8 could alleviate cognitive impairment in the APP/PS1 mouse.

Keyphrases

cognitive impairment
mouse model
coronary artery disease
cognitive decline
resting state
risk factors
cerebral ischemia