Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population.
Ching-Lung KoWei-Zhi LinMeng-Ting LeeYu-Tien ChangHung-Che LinYi-Syuan WuJun-Fu LinKe-Ting PanYu-Chuan ChangKo-Han LeeYi-Lun LeeTsung-Ting HsiehJia-Hsin HuangChih-Hung WangSung-Sen YangHsiang-Cheng ChenChi-Ming ChuPublished in: Journal of translational medicine (2022)
A total of 147 SNPs in the Taiwanese population were found to be statistically significantly associated with AS on the sixth pair of chromosomes and did not overlap with previously published sites in the GWAS Catalog. Whether those genes mapped by AS-associated SNPs are involved in AS and what the pathogenic mechanism of the mapped genes is remain to be further studied.