SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps.

Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang

Published in: Journal of immunology research (2024)

SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.

Keyphrases

chronic rhinosinusitis
poor prognosis
end stage renal disease
binding protein
anti inflammatory
chronic kidney disease
ejection fraction
long non coding rna
prognostic factors
signaling pathway
peritoneal dialysis
patient reported outcomes