Quantification of morning stiffness to assess disease activity and treatment effects in rheumatoid arthritis.
Heide BoethRobert BiesenJeremias HollnagelSandra HerrmannRainald M EhrigLorenzo PelliWilliam R TaylorGeorg N DudaFrank ButtgereitPublished in: Rheumatology (Oxford, England) (2021)
This technology allowed mechanical stiffness to be quantified in MCP joints and demonstrated high sensitivity with respect to disease status as well as medication effect in RA patients. Such non-invasive, low-risk and rapid assessment of biomechanical joint stiffness opens a novel avenue for judging therapy efficacy in patients with RA and potentially also in other non-RA inflammatory joint diseases.
Keyphrases
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- ankylosing spondylitis
- rheumatoid arthritis patients
- juvenile idiopathic arthritis
- end stage renal disease
- ejection fraction
- interstitial lung disease
- newly diagnosed
- chronic kidney disease
- prognostic factors
- healthcare
- stem cells
- idiopathic pulmonary fibrosis
- systemic sclerosis
- patient reported outcomes