Influence of probiotic supplementation on the developing microbiota in human preterm neonates.
Niels van BestSonja Trepels-KottekPaul SavelkoulThorsten OrlikowskyMathias W HornefJohn PendersPublished in: Gut microbes (2021)
Our results demonstrate successful transient colonization by probiotic bacteria and a significant influence on the endogenous microbiota with a reduced abundance of bacterial taxa associated with the development of NEC. These results emphasize that probiotic supplementation may allow targeted manipulation of the enteric microbiota and confer a clinical benefit. (Clinical Trial Registry accession number: DRKS/GCTR 00021034).