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Iron and risk of dementia: Mendelian randomisation analysis in UK Biobank.

Francesco CasanovaQu TianJanice L AtkinsAndrew R WoodDaniel WilliamsonYong QianDavid ZweibaumJun DingDavid MelzerLuigi FerrucciLuke C Pilling
Published in: Journal of medical genetics (2024)
Genetic evidence supports a causal relationship between higher TSAT and risk of clinically defined non-AD and vascular dementia, in European and African groups. This association appears to be independent of apolipoprotein-E ε4.
Keyphrases
  • mild cognitive impairment
  • cognitive impairment
  • genome wide
  • cross sectional
  • dna methylation