Lactoferrin suppresses LPS-induced expression of HMGB1, microRNA 155, 146, and TLR4/MyD88/NF-кB pathway in RAW264.7 cells.
Maryam NematiSaeideh AksehMaryam AmiriHamid Reza NejabatiAhmadreza JodatiNazila Fathi MaroufiYousef FaridvandMohammad NouriPublished in: Immunopharmacology and immunotoxicology (2021)
Altogether, these findings provide LF as a prominent anti-inflammatory agent that could modulate HMGB1, mmu-mir-155, mmu-mir-146a, and TLR4/MyD88/NF-кB pathway.
Keyphrases
- lps induced
- inflammatory response
- toll like receptor
- long non coding rna
- cell proliferation
- nuclear factor
- poor prognosis
- induced apoptosis
- anti inflammatory
- long noncoding rna
- signaling pathway
- cell cycle arrest
- immune response
- pi k akt
- oxidative stress
- cell death
- endoplasmic reticulum stress
- binding protein
- recombinant human