Inhibition and reversal of a TGF-β1 induced myofibroblast phenotype by adipose tissue-derived paracrine factors.
S HigginbothamV L WorkmanA-V GiblinNicola Helen GreenDaniel W LambertVanessa L HearndenPublished in: Stem cell research & therapy (2024)
Cultured ADSC or adipocytes have been the focus of most studies, however, this work highlights the importance of considering whole adipose tissue to further our understanding of fat grafting. This study supports the use of autologous fat grafts for scar treatment and highlights the need for further investigation to determine the mechanism.