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Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata .

Jacob F WarnerRyan BesemerAlicia SchickleErin M BorbeeIsabella V ChangsutKoty H SharpLeslie S Babonis
Published in: bioRxiv : the preprint server for biology (2023)
This study reports the development of the first transgenic knock-in coral, providing the opportunity to track the behavior of various cell types during early coral development.
Keyphrases
  • genome wide
  • copy number
  • single cell
  • genome wide identification
  • dna methylation
  • cell therapy
  • gene expression
  • genome editing
  • mesenchymal stem cells
  • transcription factor
  • bone marrow
  • drug induced