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A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector.

Javier Martínez-GarcíaManuela MolinaLeticia OdriozolaAngie MolinaGloria González-AseguinolazaNicholas D WeberCristian Smerdou
Published in: Cell & bioscience (2022)
The imPr could represent a useful tool for gene therapy approaches in which physiological BA regulation is desired.
Keyphrases
  • gene therapy
  • poor prognosis
  • dna methylation
  • gene expression
  • binding protein