Periplaneta americana extract attenuates hepatic fibrosis progression by inhibiting collagen synthesis and regulating the TGF-β1/Smad signaling pathway.
Yi ChenYanwen ZhaoLiping YuanYing HeYongshou YangPeiyun Xiao
Published in: Folia histochemica et cytobiologica (2023)
The therapeutic effect of PA-B on liver fibrosis might involve suppression of the secretion and expression of TGF-β1, regulation of the TGF-β1/Smad signaling pathway, and inhibition of collagen production and secretion.