The physiological impact of high-intensity interval training in octogenarians with comorbidities.
James E M BlackwellNima GharahdaghiMatthew S BrookShinya WatanabeCatherine L BoereboomBrett DolemanJonathan N LundDaniel J WilkinsonKenneth SmithPhilip J AthertonJohn P WilliamsBethan E PhillipsPublished in: Journal of cachexia, sarcopenia and muscle (2021)
The HIIT enhances skeletal muscle mass and CRF in octogenarians with disease, with up-regulation of MPS and mitochondrial capacity likely underlying these improvements. HIIT can be safely delivered to octogenarians with disease and is an effective, time-efficient intervention to improve muscle mass and physical function in a short time frame.