Moral conflict and competing duties in the initiation of a biomedical HIV prevention trial with minor adolescents.

Amelia S Knopf Amy Lewis GilbertGregory D ZimetBill G KapogiannisSybil G HosekJ Dennis FortenberryMary A Ottnull null

Published in: AJOB empirical bioethics (2016)

Moral conflict was resolved in a variety of ways, including reflecting on the protocol's alignment with federal regulations, modifying consent language, considering each individual for enrollment carefully, and accepting institutional review board (IRB) decisions. Potential solutions for future studies are discussed, and include flexible protocol consent procedures and centralized IRB reviews.

Keyphrases

randomized controlled trial
young adults
study protocol
physical activity
clinical trial
decision making
phase iii
current status
health insurance
healthcare
case control
risk assessment
meta analyses
open label
affordable care act