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Clinical and Molecular Characteristics Associated with Survival in Advanced Melanoma Treated with Checkpoint Inhibitors.

Sunil BadamiSunil UpadhayaRavi Kanth VelagapudiPushyami MikkilineniRanju KunworSamer A Al HadidiGhassan Bachuwa
Published in: Journal of oncology (2018)
Checkpoint inhibitors significantly increased OS in patients with wild BRAF, positive PD-1, and high LDH. However, results should be interpreted keeping in mind associated significant heterogeneity. The results of this study should help in designing future clinical trials.
Keyphrases
  • dna damage
  • clinical trial
  • cell cycle
  • single cell
  • randomized controlled trial
  • current status
  • oxidative stress
  • single molecule
  • phase ii
  • free survival