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The antioxidant capacity of erythrocyte concentrates is increased during the first week of storage and correlated with the uric acid level.

Manon BardynS MayeA LeschJ DelobelJ-D TissotF Cortés-SalazarP TacchiniN LionH H GiraultMichel Prudent
Published in: Vox sanguinis (2017)
The marked increase in AOP during the first week of storage suggests that RBCs are impacted early by the modification of their environment. The AOP behaviour reflects the changes in metabolism activity following the adjustment of the extracellular uric acid level. Knowing the origin, interdonor variability and the effects of the AOP on the RBCs could be beneficial for the storage quality, which will have to be further studied.
Keyphrases
  • uric acid
  • metabolic syndrome
  • randomized controlled trial
  • solid state
  • study protocol