Oral cancers preceded by proliferative verrucous leukoplakia exhibit distinctive molecular features.
Alejandro Herreros-PomaresAntonio José Cañada-MartínezLeticia BaganAlex ProañoDiana GarciaJuan SandovalJosé Vicente BagánPublished in: Oral diseases (2023)
PVL-OSCC patients presented lower expression of cancer-related genes. Hypermethylation of the promoter region of many genes was also noticed, indicating that DNA methylation could be a regulatory mechanism.