miR-26b-5p helps in EpCAM+cancer stem cells maintenance via HSC71/HSPA8 and augments malignant features in HCC.
Ritu KhoslaHamed HematiArchana RastogiGayatri RamakrishnaShiv Kumar SarinNirupama TrehanpatiPublished in: Liver international : official journal of the International Association for the Study of the Liver (2019)
miR-26b-5p imparts metastatic properties and helps in maintenance of Ep+ CSCs via HSPA8. Thus, miR-26b-5p and HSPA8 could serve as molecular targets for selectively eliminating the Ep+ CSC population in human HCCs.