Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features.
Jennifer G GoldmanHoward AndrewsAmy AmaraAnna NaitoRoy N AlcalayLeslie M ShawPeggy TaylorTao XiePaul TuiteClaire HenchcliffePenelope HogarthSamuel FrankMarie-Helene Saint-HilaireMark FrasierVanessa ArnedoAlyssa N ReimerMargaret SutherlandChristine Swanson-FischerKatrina Gwinnnull nullUn Jung KangPublished in: Movement disorders : official journal of the Movement Disorder Society (2017)
Lower CSF alpha-synuclein is associated with diagnosis and motor phenotype in moderate-advanced PD. Plasma and saliva alpha-synuclein neither correlate with CSF alpha-synuclein, nor distinguish PD from controls. CSF beta-amyloid1-42 remains a potential biomarker for cognitive impairment in PD. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.