Long-Term Voluntary Physical Exercise Exerts Neuroprotective Effects and Motor Disturbance Alleviation in a Rat Model of Parkinson's Disease.
Wan-Ling TsaiHsin-Yung ChenYing-Zu HuangYuan-Hao ChenChi-Wei KuoTsung-Hsun HsiehTsung-Hsun HsiehPublished in: Behavioural neurology (2019)
Our results demonstrated that long-term exercise training is effective for neuroprotection and further attenuates motor declines induced by 6-OHDA in an experimental model of PD. Our data further highlighted potential therapeutic effects of long-term physical exercise relevant to clinical effects for further potential application on human PD subjects.