A Translational Study on Acute Traumatic Brain Injury: High Incidence of Epileptiform Activity on Human and Rat Electrocorticograms and Histological Correlates in Rats.

Ilia G KomoltsevMikhail Vladimirovich SinkinAleksandra A VolkovaElizaveta A SmirnovaMargarita R NovikovaOlga O KordonskayaAlexander E TalypovAlla B GuekhtVladimir V Krylov Natalia V Gulyaeva

Published in: Brain sciences (2020)

Epileptiform activity is frequent in the acute period of TBI period and is associated with distant hippocampal damage on a microscopic level. This damage is probably involved in late consequences of TBI. The FPI model is suitable for exploring pathogenetic mechanisms of post-traumatic disorders.

Keyphrases

traumatic brain injury
liver failure
oxidative stress
respiratory failure
severe traumatic brain injury
endothelial cells
drug induced
aortic dissection
risk factors
hepatitis b virus
intensive care unit
pluripotent stem cells
subarachnoid hemorrhage
brain injury