The impact of glucagon and exenatide on oxidative stress levels and antioxidative enzyme expression in in vitro induced steatosis in HepG2 cell culture.
Aleksandra BołdysŁukasz BułdakEstera SkudrzykGrzegorz MachnikBogusław OkopieńPublished in: Endokrynologia Polska (2024)
Combined activation of glucagon-like peptide-1 (GLP-1) and glucagon receptors reduces oxidative stress in HepG2 steatotic cell cultures. This observation may stem from increased antioxidative potential.
Keyphrases
- oxidative stress
- diabetic rats
- poor prognosis
- anti inflammatory
- dna damage
- ischemia reperfusion injury
- single cell
- induced apoptosis
- cell therapy
- insulin resistance
- high glucose
- drug induced
- type diabetes
- stem cells
- metabolic syndrome
- long non coding rna
- mesenchymal stem cells
- endothelial cells
- high fat diet induced
- adipose tissue
- stress induced