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Distribution of pathogenic variants in the CFTR gene in a representative cohort of people with cystic fibrosis in the Kingdom of Bahrain.

Osama A Karim MajedFatema Osama MajedNabeel Jasim AlmoamenHusain Baqer AlsatrawiSalma Dawood ShehabiJana HrbkováMalgorzata LibikMilan Macek
Published in: Molecular genetics and genomics : MGG (2024)
The most commonCF-causing  mutations in Bahraini pwCF were identified, enabling more precise diagnosis, introduction of two-tier neonatal screening and fostering administration of CFTRm.
Keyphrases
  • cystic fibrosis
  • copy number
  • pseudomonas aeruginosa
  • lung function
  • genome wide
  • cross sectional
  • genome wide identification
  • dna methylation
  • chronic obstructive pulmonary disease