Systems biology analysis of publicly available transcriptomic data reveals a critical link between AKR1B10 gene expression, smoking and occurrence of lung cancer.

Juan M Cubillos-AnguloEduardo R FukutaniLuís A B CruzMaría B ArriagaJoão Victor LimaBruno Bezerril AndradeArtur T L QueirozKiyoshi F Fukutani

Published in: PloS one (2020)

The systematic analysis of transcriptomic studies performed here revealed a potential critical link between AKR1B10 expression, smoking and occurrence of lung cancer.

Keyphrases

single cell
gene expression
risk assessment
smoking cessation
rna seq
poor prognosis
dna methylation
human health
electronic health record
big data
case control
long non coding rna
deep learning