The possible role of CD8+/Vα7.2+/CD161++ T (MAIT) and CD8+/Vα7.2+/CD161lo T (MAIT-like) cells in the pathogenesis of early-onset pre-eclampsia.

Matyas MeggyesJulia SzantoAdrienn LajkoBalint FarkasAkos VarnagyPeter TamasEszter HantosiEva MikoLaszlo Szereday

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2017)

Altered frequency and reduced PD-1 expression combined together with the elevated perforin content of MAIT cells insinuate their potential roles in the pathogenesis of early-onset pre-eclampsia.

Keyphrases

early onset
late onset
nk cells
induced apoptosis
poor prognosis
risk assessment
signaling pathway
cell death
endoplasmic reticulum stress