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Predisposing factors and clinical impact of high-output syndrome after sphincter-preserving surgery with covering ileostomy for rectal cancer: a retrospective single-center cohort study.

Ryota NakanishiTsuyoshi KonishiErika NakayaYoko ZaitsuToshiki MukaiTomohiro YamaguchiToshiya NagasakiTakashi AkiyoshiSatoshi NagayamaYosuke Fukunaga
Published in: International journal of clinical oncology (2020)
Preoperative (chemo)radiotherapy, postoperative inflammatory response, and postoperative complications predisposed to high-output syndrome, and it significantly impacted postoperative renal dysfunction. Active monitoring and early intervention are warranted to prevent renal dysfunction in patients with these factors.
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