Nationwide experience of catecholaminergic polymorphic ventricular tachycardia caused by RyR2 mutations.
Anders Krogh BroendbergJens Cosedis NielsenJesper BjerreLisbeth Noerum PedersenJens KristensenFinn Lund HenriksenHenning BundgaardHenrik Kjaerulf JensenPublished in: Heart (British Cardiac Society) (2017)
In a national cohort of RyR2 mutation-positive CPVT patients, SCD, ASCD and syncope were presenting events in the majority of probands and also occurred in 36% of relatives identified through family screening. Probands were younger at disease onset and more prone to fatal or near-fatal events than relatives.