Mobile-health intervention for smoking cessation among Cambodian people living with HIV: A mixed-methods pilot study.
Thanh Cong BuiHeng SopheabMichael S BusinelleChhorvann ChheaSun Penh LyJennifer I VidrineDawin TholSummer Frank-PearceDamon J VidrinePublished in: AIDS care (2021)
This mixed methods study aimed to evaluate the feasibility and preliminary efficacy of a fully automated, interactive smartphone-delivered intervention for smoking cessation among people living with HIV in Cambodia. We used the explanatory sequential design, with a pilot two-group single-blind randomized controlled trial (N = 50) followed by in-depth interviews with all trial participants. In the trial, participants were randomized to Standard Care (SC) or Automated Messaging (AM) group. SC comprised brief advice to quit and self-help materials. AM consisted of the SC components plus a fully automated smartphone-based treatment program that involved interactive and tailored proactive messaging for 2 months. Results showed that the AM approach was highly feasible and efficacious. Feasibility was supported by high rates of treatment engagement (e.g., 81% of delivered messages and assessments were read or completed) and high retention (96%) through the 2-month follow-up. Biochemically verified point prevalence abstinence at follow-up was 40% for the AM group and 8% for the SC group (relative risk: 5.0, 95% confidence interval: 1.2, 20.5). Being able to avoid other smokers, having coping skills, and having social/familial support contributed to successful abstinence. The AM program has the potential for wide-scale implementation in Cambodia and other low-income countries.
Keyphrases
- smoking cessation
- study protocol
- randomized controlled trial
- replacement therapy
- quality improvement
- healthcare
- phase iii
- machine learning
- open label
- high throughput
- clinical trial
- phase ii
- double blind
- placebo controlled
- risk factors
- systematic review
- palliative care
- optical coherence tomography
- pain management
- mental health
- affordable care act