Darbepoetin administration to neonates undergoing cooling for encephalopathy: a safety and pharmacokinetic trial.

Mariana C BasergaJoanna C BeachyJessica K RobertsRobert M WardRobert J DiGeronimoWilliam F WalshRobin K OhlsJennifer AndersonDennis E MayockChristopher M TraudtRobert D ChristensenManndi C LoertscherChris StockmannCatherine M T SherwinMichael G SpigarelliBradley A Yoder

Published in: Pediatric research (2015)

Darbe combined with hypothermia has similar safety profile to placebo with pharmacokinetics sufficient for weekly administration.

Keyphrases

phase iii
cardiac arrest
clinical trial
study protocol
early onset
brain injury
randomized controlled trial
double blind
preterm birth