The impact of sex on treatment and outcome in relation to histological subtype in patients with resectable gastric cancer: Results from the randomized CRITICS trial.
Irene A CaspersAstrid E SlagterPehr LindKarolina SikorskaKatja WiklundFredrik PonténMarianne NordsmarkCornelis J H van de VeldeElma Meershoek-Klein KranenbargJohanna W van SandickEdwin P M JansenHanneke W M van LaarhovenMarcel VerheijNicole C T van GriekenAnnemieke CatsPublished in: Journal of surgical oncology (2023)
Positive distal margin rates were higher in females with diffuse GC, predominantly at the duodenal site. Females also experience more toxicity, but this neither impacts dose intensities nor surgical resection rates. Clinicians should be aware of these different surgical outcomes when treating males and females with GC.