Transcriptional analysis identifies potential novel biomarkers associated with successful ex-vivo perfusion of human donor lungs.

John Robert FerdinandMorvern Isabel MorrisonAnders AndreassonCatriona CharltonAlisha Kaur ChhatwalWilliam Earl ScottLee Anthony BorthwickMenna Ruth ClatworthyAndrew J Fisher

Published in: Clinical transplantation (2022)

Together, our data identify novel biomarkers that may assist with pre-transplant lung assessment, as well as pathways that may be amenable to therapeutic intervention during EVLPAQ6.

Keyphrases

endothelial cells
randomized controlled trial
electronic health record
genome wide
transcription factor
big data
induced pluripotent stem cells
contrast enhanced
risk assessment
oxidative stress
heat shock
deep learning