Rho and Rac, but not ROCK, are required for secretion of human and mouse eosinophil-associated RNases.

Revital ShamriKristen M YoungPeter F Weller

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)

Collectively, these data suggest a cytoskeleton-dependent mechanism of EAR secretion from eosinophils, findings that are pertinent to host defence, allergy and other eosinophil-associated diseases.

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