Adverse prognosis of glioblastoma contacting the subventricular zone: Biological correlates.
Sharon BerendsenEmma J van BodegravenTatjana SeuteWim G M SplietMarjolein GeurtsJeroen HendrikseLaurent SchoysmanWillemijn B HuiszoonMeri VarkilaSoufyan RoussErica H BellJérôme KroonenArnab ChakravartiVincent BoursTom J SnijdersPierre A RobePublished in: PloS one (2019)
In conclusion, involvement of the SVZ is an independent prognostic factor in glioblastoma, and associates with increased expression of key markers of (epithelial-) mesenchymal transformation, but does not correlate with stem cellness, molecular subtype, or specific (mi)RNA expression patterns.