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Galectin 3 expression in regional lymph nodes and lymph node metastases of oral squamous cell carcinomas.

Falk WehrhanMaike Büttner-HeroldLuitpold DistelJutta RiesPatrick MoebiusRaimund PreidlCarol I GeppertFriedrich W NeukamMarco KestingManuel Weber
Published in: BMC cancer (2018)
Gal3 expression in regional lymph nodes might be associated with oscc progression. The increased Gal3 expression in regional lymph nodes of larger tumors underlines the need of immunomodulatory treatment concepts in early-stage oscc. Blocking of Gal3 might be a therapeutic option in oral cancer.
Keyphrases
  • lymph node
  • poor prognosis
  • sentinel lymph node
  • early stage
  • neoadjuvant chemotherapy
  • squamous cell
  • long non coding rna
  • squamous cell carcinoma
  • high grade
  • radiation therapy
  • replacement therapy