Long non-coding RNA MAPKAPK5-AS1/PLAGL2/HIF-1α signaling loop promotes hepatocellular carcinoma progression.

Liang WangLiankang SunRunkun LiuHuanye MoYongshen NiuTianxiang ChenYufeng WangShaoshan HanKangsheng TuQingguang Liu

Published in: Journal of experimental & clinical cancer research : CR (2021)

Our results reveal a MAPKAPK5-AS1/PLAGL2/HIF-1α signaling loop in HCC progression and suggest that MAPKAPK5-AS1 could be a potential novel therapeutic target of HCC.

Keyphrases

long non coding rna
poor prognosis
transcription factor
endothelial cells
genome wide
gene expression
single cell
human health
risk assessment
climate change