Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a.

Yajing LiuSensen LouJinhui LiYuanhua LiuShisheng HuangYu WeiJikai LiuRuimin LvJunjie TangZhixin ShenYidi SunXing-Xu HuangZhiqi XiongHui YangChangyang Zhou

Published in: Cell discovery (2024)

Keyphrases

crispr cas
dna methylation
high fat diet induced
gene expression
case report
mouse model
wild type
insulin resistance
adipose tissue
skeletal muscle