Xing-Xu Huang (Xingxu Huang)

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 41

Top Venues

Nature communications

Cell research

Cell death and differentiation

Cell death & disease

ShanghaiTech University

Southern Medical University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

ShanghaiTech University

China

Professor :: School of Life Science and Technology

Education History

Southern Medical University

China

PHD

Publications

Hongyuan Zhang, Jiacheng Ma, Zhaowei Wu, Xiaoyang Chen, Yangyang Qian, Weizhong Chen, Zhipeng Wang, Ya Zhang, Huanhu Zhu, Xing-Xu Huang, Quanjiang Ji
BacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases. Nature communications 15 (1) (2024)
Guo Li, Yaxian Cheng, Jingwen Yu, Yunfei Zhu, Hongru Ma, Yuqiao Zhou, Zhongji Pu, Guanglin Zhu, Yichen Yuan, Ziyue Zhang, Xinzhi Zhou, Kairen Tian, Jianjun Qiao, Xiaoxiang Hu, Xue-Xin Chen, Quanjiang Ji, Xing-Xu Huang, Bin Ma, Yuan Yao
Compact RNA editors with natural miniature Cas13j nucleases. Nature chemical biology (2024)
Peng Cheng, Cong Mao, Jin Tang, Sen Yang, Yu Cheng, Wuke Wang, Qiuxi Gu, Wei Han, Hao Chen, Sihan Li, Yaofeng Chen, Jianglin Zhou, Wuju Li, Aimin Pan, Suwen Zhao, Xing-Xu Huang, Shiqiang Zhu, Jun Zhang, Wenjie Shu, Shengqi Wang
Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering. Cell research (2024)
Yin Liu, Xinyi Liu, Dongyi Wei, Lu Dang, Xiaoran Xu, Shisheng Huang, Liwen Li, Sanyun Wu, Jinxian Wu, Xiaoyan Liu, Wenjun Sun, Wanyu Tao, Yongchang Wei, Xing-Xu Huang, Kui Li, Xinjie Wang, Fuling Zhou
CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels. Nature communications 15 (1) (2024)
Yin Liu, Xinyi Liu, Dongyi Wei, Lu Dang, Xiaoran Xu, Shisheng Huang, Liwen Li, Sanyun Wu, Jinxian Wu, Xiaoyan Liu, Wenjun Sun, Wanyu Tao, Yongchang Wei, Xing-Xu Huang, Kui Li, Xinjie Wang, Fuling Zhou
CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels. Nature communications 15 (1) (2024)
Fei Du, Zijia Li, Xin Li, Duoduo Zhang, Feng Zhang, Zixu Zhang, Yingshuang Xu, Jin Tang, Yongqian Li, Xing-Xu Huang, Yang Gu, Xiao-Man Sun, He Huang
Optimizing multicopy chromosomal integration for stable high-performing strains. Nature chemical biology (2024)
Yajing Liu, Sensen Lou, Jinhui Li, Yuanhua Liu, Shisheng Huang, Yu Wei, Jikai Liu, Ruimin Lv, Junjie Tang, Zhixin Shen, Yidi Sun, Xing-Xu Huang, Zhiqi Xiong, Hui Yang, Changyang Zhou
Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a. Cell discovery 10 (1) (2024)
Peng Cheng, Cong Mao, Jin Tang, Sen Yang, Yu Cheng, Wuke Wang, Qiuxi Gu, Wei Han, Hao Chen, Sihan Li, Yaofeng Chen, Jianglin Zhou, Wuju Li, Aimin Pan, Suwen Zhao, Xing-Xu Huang, Shiqiang Zhu, Jun Zhang, Wenjie Shu, Shengqi Wang
Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering. Cell research 34 (9) (2024)
Wei Han, Siyu Bao, Jintao Liu, Yiran Wu, Liting Zeng, Tao Zhang, Ningmeng Chen, Kai Yao, Shunguo Fan, Aiping Huang, Yuanyuan Feng, Guiquan Zhang, Ruiyi Zhang, Hongjin Zhu, Tian Hua, Zhijie Liu, Lina Cao, Xing-Xu Huang, Suwen Zhao
CORD: The chordata olfactory receptor database. Protein & cell (2024)
Yin Liu, Xinyi Liu, Dongyi Wei, Lu Dang, Xiaoran Xu, Shisheng Huang, Liwen Li, Sanyun Wu, Jinxian Wu, Xiaoyan Liu, Wenjun Sun, Wanyu Tao, Yongchang Wei, Xing-Xu Huang, Kui Li, Xinjie Wang, Fuling Zhou
CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels. Nature communications 15 (1) (2024)
Hongyuan Zhang, Jiacheng Ma, Zhaowei Wu, Xiaoyang Chen, Yangyang Qian, Weizhong Chen, Zhipeng Wang, Ya Zhang, Huanhu Zhu, Xing-Xu Huang, Quanjiang Ji
BacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases. Nature communications 15 (1) (2024)
Hongyuan Zhang, Jiacheng Ma, Zhaowei Wu, Xiaoyang Chen, Yangyang Qian, Weizhong Chen, Zhipeng Wang, Ya Zhang, Huanhu Zhu, Xing-Xu Huang, Quanjiang Ji
BacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases. Nature communications 15 (1) (2024)
Xianlei Li, Ningqiang Gong, Falin Tian, Shangkun Zhang, Yuxuan Zhang, Yufei Wang, Guangchao Qing, Yongchao Wang, Fangzhou Li, Yihui Xu, Linlin Zhang, Jinjin Wang, Qiankun Ni, Yaling Gan, Chaojiang Gu, Huaidong Jiang, Xing-Xu Huang, Xinghua Shi, Tongcun Zhang, Yan Wu, Xing-Jie Liang
Suppression of cytokine release syndrome during CAR-T-cell therapy via a subcutaneously injected interleukin-6-adsorbing hydrogel. Nature biomedical engineering (2023)
Xiangyang Li, Guiquan Zhang, Shisheng Huang, Yao Liu, Jin Tang, Mingtian Zhong, Xin Wang, Wenjun Sun, Yuan Yao, Quanjiang Ji, Xiaolong Wang, Jianghuai Liu, Shiqiang Zhu, Xing-Xu Huang
Development of a versatile nuclease prime editor with upgraded precision. Nature communications 14 (1) (2023)
Xiangyang Li, Guiquan Zhang, Shisheng Huang, Yao Liu, Jin Tang, Mingtian Zhong, Xin Wang, Wenjun Sun, Yuan Yao, Quanjiang Ji, Xiaolong Wang, Jianghuai Liu, Shiqiang Zhu, Xing-Xu Huang
Development of a versatile nuclease prime editor with upgraded precision. Nature communications 14 (1) (2023)
Xiangyang Li, Guiquan Zhang, Shisheng Huang, Yao Liu, Jin Tang, Mingtian Zhong, Xin Wang, Wenjun Sun, Yuan Yao, Quanjiang Ji, Xiaolong Wang, Jianghuai Liu, Shiqiang Zhu, Xing-Xu Huang
Development of a versatile nuclease prime editor with upgraded precision. Nature communications 14 (1) (2023)
Xiangyang Li, Guiquan Zhang, Shisheng Huang, Yao Liu, Jin Tang, Mingtian Zhong, Xin Wang, Wenjun Sun, Yuan Yao, Quanjiang Ji, Xiaolong Wang, Jianghuai Liu, Shiqiang Zhu, Xing-Xu Huang
Development of a versatile nuclease prime editor with upgraded precision. Nature communications 14 (1) (2023)
Guo Li, Xiaoning Zhu, Yihan Wang, Hongru Ma, Yuzhe Wang, Hanyu Wu, Xiangyang Li, Yiling Wang, Jianen Gao, Xue-Xin Chen, Xing-Xu Huang, Yuan Yao, Xiaoxiang Hu
Transcription-wide impact by RESCUE-induced off-target single nucleotide variants in mammalian cell. Journal of molecular cell biology (2023)
Fenyong Yao, Shisheng Huang, Jiahui Liu, Chunhua Tan, Mengqi Xu, Dengkui Wang, Maoqing Huang, Yiyao Zhu, Xing-Xu Huang, Shuijin He
Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell death & disease 14 (8) (2023)
Xiangyang Li, Guiquan Zhang, Shisheng Huang, Yao Liu, Jin Tang, Mingtian Zhong, Xin Wang, Wenjun Sun, Yuan Yao, Quanjiang Ji, Xiaolong Wang, Jianghuai Liu, Shiqiang Zhu, Xing-Xu Huang
Development of a versatile nuclease prime editor with upgraded precision. Nature communications 14 (1) (2023)
Xuelong Yao, Zongyang Lu, Zhanying Feng, Lei Gao, Xin Zhou, Min Li, Suijuan Zhong, Qian Wu, Zhenbo Liu, Haofeng Zhang, Zeyuan Liu, Lizhi Yi, Tao Zhou, Xudong Zhao, Jun Zhang, Yong Wang, Xing-Xu Huang, Xiaoqun Wang, Jiang Liu
Comparison of chromatin accessibility landscapes during early development of prefrontal cortex between rhesus macaque and human. Nature communications 13 (1) (2022)
Haohao Zhang, Yiming Hu, Dandan Liu, Zhi Liu, Ningxia Xie, Sanhong Liu, Jie Zhang, Yuhang Jiang, Cuifeng Li, Qi Wang, Xi Chen, Deji Ye, Donglin Sun, Yujia Zhai, Xinhui Yan, Yongzhong Liu, Charlie Degui Chen, Xing-Xu Huang, Y Eugene Chin, Yufang Shi, Baojin Wu, Xiaoren Zhang
The histone demethylase Kdm6b regulates the maturation and cytotoxicity of TCRαβ + CD8αα + intestinal intraepithelial lymphocytes. Cell death and differentiation 29 (7) (2022)
Zhean Li, Lingling Luo, Wenxia Yu, Ping Li, Danfeng Ou, Jia Liu, Hanhui Ma, Qinhu Sun, Aibin Liang, Cheng Huang, Tian Chi, Xing-Xu Huang, Yu Zhang
PPARγ phase separates with RXRα at PPREs to regulate target gene expression. Cell discovery 8 (1) (2022)
Yafeng Wang, Guiquan Zhang, Qingzhou Meng, Shisheng Huang, Panpan Guo, Qibin Leng, Lingyun Sun, Geng Liu, Xing-Xu Huang, Jianghuai Liu
Precise tumor immune rewiring via synthetic CRISPRa circuits gated by concurrent gain/loss of transcription factors. Nature communications 13 (1) (2022)
Guiquan Zhang, Yao Liu, Shisheng Huang, Shiyuan Qu, Daolin Cheng, Yuan Yao, Quanjiang Ji, Xiaolong Wang, Xing-Xu Huang, Jianghuai Liu
Enhancement of prime editing via xrRNA motif-joined pegRNA. Nature communications 13 (1) (2022)
Yuan Zong, Yijing Liu, Chenxiao Xue, Boshu Li, Xiangyang Li, Yanpeng Wang, Ji Li, Guanwen Liu, Xing-Xu Huang, Xiaofeng Cao, Caixia Gao
An engineered prime editor with enhanced editing efficiency in plants. Nature biotechnology 40 (9) (2022)
Xiangyang Li, Xin Wang, Wenjun Sun, Shisheng Huang, Mingtian Zhong, Yuan Yao, Quanjiang Ji, Xing-Xu Huang
Enhancing prime editing efficiency by modified pegRNA with RNA G-quadruplexes. Journal of molecular cell biology 14 (4) (2022)
Ying Xue, Min Li, Jie Hu, Yuanlin Song, Wei Guo, Changhong Miao, Di Ge, Yingyong Hou, Xuefei Wang, Xing-Xu Huang, Tianshu Liu, Xiaoping Zhang, Qihong Huang
Ca v 2.2-NFAT2-USP43 axis promotes invadopodia formation and breast cancer metastasis through cortactin stabilization. Cell death & disease 13 (9) (2022)
Qian Zhang, Ziting Chen, Fangzhu Wang, Siqi Zhang, Hongyu Chen, Xueying Gu, Fengcai Wen, Jiachuan Jin, Xia Zhang, Xing-Xu Huang, Bin Shen, Bo Sun
Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer. Nucleic acids research 49 (21) (2022)
Dong-Dong Qin, Jian-Kui Zhou, Xie-Chao He, Xiang-Yu Shen, Cong Li, Huan-Zhi Chen, Lan-Zhen Yan, Zheng-Fei Hu, Xiang Li, Long-Bao Lv, Yong-Gang Yao, Zheng Wang, Xing-Xu Huang, Xin-Tian Hu, Ping Zheng
Depletion of giant ANK2 in monkeys causes drastic brain volume loss. Cell discovery 7 (1) (2021)
Jianan Li, Wenxia Yu, Shisheng Huang, Susu Wu, Liping Li, Jiankui Zhou, Yu Cao, Xing-Xu Huang, Yunbo Qiao
Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity. Nature communications 12 (1) (2021)
Lijie Wang, Wei Xue, Hongxia Zhang, Runze Gao, Houyuan Qiu, Jia Wei, Lina Zhou, Yun-Ni Lei, Xiaocheng Wu, Xiao Li, Chengfang Liu, Jing Wu, Qiubing Chen, Hanhui Ma, Xing-Xu Huang, Cheguo Cai, Ying Zhang, Bei Yang, Hao Yin, Li Yang, Jia Chen
Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations. Nature cell biology 23 (5) (2021)
Xinjie Wang, Xiaoyun Shang, Xing-Xu Huang
Next-generation pathogen diagnosis with CRISPR/Cas-based detection methods. Emerging microbes & infections 9 (1) (2021)
Tao Liu, Xinfeng Zheng, Chenglong Wang, Chuandong Wang, Sheng-Dan Jiang, Bo Li, Peng-Bo Chen, Wenning Xu, Huoliang Zheng, Runze Yang, Xing-Xu Huang, Xiaoling Zhang, Lei-Sheng Jiang
The m6A "reader" YTHDF1 promotes osteogenesis of bone marrow mesenchymal stem cells through translational control of ZNF839. Cell death & disease 12 (11) (2021)
Minglei Zhi, Jinying Zhang, Qianzi Tang, Dawei Yu, Shuai Gao, Dengfeng Gao, Pengliang Liu, Jianxiong Guo, Tang Hai, Jie Gao, Suying Cao, Zimo Zhao, Chongyang Li, Xiaogang Weng, Mengnan He, Tianzhi Chen, Yingjie Wang, Keren Long, Deling Jiao, Guanglei Li, Jiaman Zhang, Yan Liu, Yu Lin, Daxin Pang, Qianqian Zhu, Naixin Chen, Jingjing Huang, Xinze Chen, Yixuan Yao, Jingcang Yang, Zicong Xie, Xianya Huang, Mengxin Liu, Ran Zhang, Qiuyan Li, Yi-Liang Miao, Jianhui Tian, Xing-Xu Huang, Hongsheng Ouyang, Bofeng Liu, Wei Xie, Qi Zhou, Hong-Jiang Wei, Zhonghua Liu, Caihong Zheng, Mingzhou Li, Jianyong Han
Generation and characterization of stable pig pregastrulation epiblast stem cell lines. Cell research (2021)
Yiming Hu, Haohao Zhang, Ningxia Xie, Dandan Liu, Yuhang Jiang, Zhi Liu, Deji Ye, Sanhong Liu, Xi Chen, Cuifeng Li, Qi Wang, Xing-Xu Huang, Yongzhong Liu, Yufang Shi, Xiaoren Zhang
Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1. Cell death and differentiation (2021)
Yao Liu, Guang Yang, Shuhong Huang, Xiangyang Li, Xin Wang, Guanglei Li, Tian Chi, Yulin Chen, Xing-Xu Huang, Xiaolong Wang
Enhancing prime editing by Csy4-mediated processing of pegRNA. Cell research 31 (10) (2021)
Lu Dang, Guanglei Li, Xinjie Wang, Shisheng Huang, Yu Zhang, Yuanxin Miao, Lisi Zeng, Shu-Zhong Cui, Xing-Xu Huang
Comparison of gene disruption induced by cytosine base editing-mediated iSTOP with CRISPR/Cas9-mediated frameshift. Cell proliferation 53 (5) (2020)
Yajing Liu, Changyang Zhou, Shisheng Huang, Lu Dang, Yu Wei, Jun He, Yingsi Zhou, Shaoshuai Mao, Wanyu Tao, Yu Zhang, Hui Yang, Xing-Xu Huang, Tian Chi
A Cas-embedding strategy for minimizing off-target effects of DNA base editors. Nature communications 11 (1) (2020)
Peixiang Ma, Qingzhou Meng, Baoqing Sun, Bing Zhao, Lu Dang, Mingtian Zhong, Siyuan Liu, Hongtao Xu, Hong Mei, Jia Liu, Tian Chi, Guang Yang, Ming Liu, Xing-Xu Huang, Xinjie Wang
MeCas12a, a Highly Sensitive and Specific System for COVID-19 Detection. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2020)
Li-Zong Rao, Yi Wang, Lei Zhang, Guorao Wu, Lu Zhang, Fa-Xi Wang, Long-Min Chen, Fei Sun, Song Jia, Shu Zhang, Qilin Yu, Jiang-Hong Wei, Hui-Ren Lei, Ting Yuan, Jinxiu Li, Xing-Xu Huang, Bin Cheng, Jianping Zhao, Yongjian Xu, Bi-Wen Mo, Cong-Yi Wang, Huilan Zhang
IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages. Cell death and differentiation 28 (4) (2020)

Xing-Xu Huang.css-eqlu8i{font-size:small;padding-left:4px;} (Xingxu Huang)

Publication Activity (10 Years)

Top Topics

Top Venues

Xing-Xu Huang (Xingxu Huang)