Pilot randomized controlled trial on early and late remote ischemic preconditioning prior to complex cardiac surgery in young infants.
Gonzalo Garcia GuerraAri R JoffeRob SealErnest PhilliposMaggie WongElham Khodayari MoezIrina A DinuJonathan P DuffDavid RossIvan RebeykaCharlene M T RobertsonPublished in: Paediatric anaesthesia (2017)
In infants who underwent surgery for congenital heart disease, our pilot randomized controlled trial on early and late remote ischemic preconditioning proved to be feasible but did not find any significant difference in acute outcomes. A larger trial may be necessary.
Keyphrases
- study protocol
- randomized controlled trial
- congenital heart disease
- ischemia reperfusion injury
- cerebral ischemia
- cardiac surgery
- clinical trial
- minimally invasive
- liver failure
- open label
- acute kidney injury
- subarachnoid hemorrhage
- coronary artery bypass
- oxidative stress
- respiratory failure
- blood brain barrier
- brain injury
- drug induced
- systematic review
- placebo controlled
- hepatitis b virus
- adipose tissue
- middle aged
- phase iii
- coronary artery disease
- glycemic control
- acute coronary syndrome
- insulin resistance
- mechanical ventilation