A Population-Based Study of the Bidirectional Association Between Obstructive Sleep Apnea and Type 2 Diabetes in Three Prospective U.S. Cohorts.

Tianyi HuangBrian M LinMeir J StampferShelley T TworogerFrank B HuSusan Redline

Published in: Diabetes care (2018)

OSA is independently associated with an increased risk of diabetes, whereas insulin-treated diabetes is independently associated with a higher risk of OSA, particularly in women. Clinical awareness of this bidirectional association may improve prevention and treatment of both diseases. Future research aimed at elucidating the mechanisms that underlie each association may identify novel intervention targets.

Keyphrases

type diabetes
obstructive sleep apnea
glycemic control
positive airway pressure
cardiovascular disease
randomized controlled trial
insulin resistance
polycystic ovary syndrome
sleep apnea
metabolic syndrome
pregnant women
skeletal muscle
current status
weight loss