Tenascin-C-mediated suppression of extracellular matrix adhesion force promotes entheseal new bone formation through activation of Hippo signalling in ankylosing spondylitis.
Zihao LiSiwen ChenHaowen CuiXiang LiDongying ChenWenjun HaoJianru WangZemin LiZhaomin ZhengZhongping ZhangHui LiuPublished in: Annals of the rheumatic diseases (2021)
Inflammation-induced aberrant expression of TNC by FSP1+fibroblasts promotes entheseal new bone formation by suppressing ECM adhesion forces and activating Hippo signalling.
Keyphrases
- extracellular matrix
- ankylosing spondylitis
- rheumatoid arthritis
- disease activity
- poor prognosis
- oxidative stress
- biofilm formation
- diabetic rats
- high glucose
- signaling pathway
- single molecule
- cell migration
- drug induced
- escherichia coli
- staphylococcus aureus
- binding protein
- long non coding rna
- endothelial cells
- cell adhesion