PRimary Care Opioid Use Disorders treatment (PROUD) trial protocol: a pragmatic, cluster-randomized implementation trial in primary care for opioid use disorder treatment.
Cynthia I CampbellAndrew J SaxonDenise M BoudreauPaige D WartkoJennifer F BobbAmy K LeeAbigail G MatthewsJennifer McCormackDavid S LiuMegan AddisAndrea AltschulerJeffrey H SametColleen T LaBelleJulia ArnstenRyan M CaldeiroDouglas T BorstAngela L StottsJordan M BraciszewskiJosé SzapocznikGavin BartRobert P SchwartzJennifer McNeelyJane M LiebschutzJudith I TsuiJoseph O MerrillJoseph E GlassGwen T LaphamSean M MurphyZoe M WeinsteinBobbi Jo H YarboroughKatharine A BradleyPublished in: Addiction science & clinical practice (2021)
The PROUD trial provides information for clinical leaders and policy makers regarding potential benefits for patients and health systems of a collaborative care model for management of OUD in primary care, tested in real-world diverse primary care settings. Trial registration # NCT03407638 (February 28, 2018); CTN-0074 https://clinicaltrials.gov/ct2/show/NCT03407638?term=CTN-0074&draw=2&rank=1.
Keyphrases
- primary care
- phase iii
- study protocol
- phase ii
- clinical trial
- open label
- healthcare
- randomized controlled trial
- general practice
- quality improvement
- end stage renal disease
- double blind
- placebo controlled
- ejection fraction
- public health
- chronic kidney disease
- newly diagnosed
- mental health
- palliative care
- preterm infants
- magnetic resonance imaging
- positron emission tomography
- smoking cessation
- preterm birth